The Department of Biology emphasizes several broad areas of Biology including Cell and Molecular Biology, Conservation Biology, Genetics, Ecology, Evolution, Medical Entomology, and Physiology. The Department has approximately 600 majors and 50 graduate students. The active research programs of the Biology faculty offer both undergraduate and Master of Science students the opportunity to learn while making contributions to research projects of regional, national and international significance. Georgia Southern Biology graduates are employed by federal and state agencies like the CDC, USDA, EPA or DNR, and others work in industry, doing biomedical testing, developing biomedical products, or consulting on ecological/environmental issues. Many develop careers at universities and colleges, while others teach in public or private secondary schools. Biology pre-professional programs in medicine, dentistry, optometry (and other para-medical fields), forestry and veterinary science offer additional career alternatives.

The Department of Biology houses a variety of laboratory and field equipment for faculty and student research including both scanning and transmission electron microscopes, a greenhouse and herbarium, and a graduate student computer laboratory. Adding to the available resources on campus are the Botanical Garden, Center for Wildlife Education, and the internationally recognized Institute of Arthropodology and Parasitology. Active collaborations with the Skidaway Oceanographic Institute and the Georgia Marine Extension have also been developed.

The University's location in the coastal plain ecosystem provides students with the opportunity to conduct research in a variety of habitats including sandhills, forests, marshes, and cypress swamps. Of particular note is the 200 km band of salt marshes which extend along the length of the Georgia coast from the Savannah River to the St. Mary's. This complex ecosystem provides a habitat for many of the rare and endangered species of the state. Some faculty and their students also carry out research projects at other off-campus sites, including the tropics, coral reefs, and field research and biological stations across the U.S.

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